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SEVENTH FRAMEWORK PROGRAMME

The Group - Consortium - Medizinische Hochschule Hannover

Stifung Tierärztliche Hochschule Hannover

Hannover Medical School
Institute of Clinical Pharmacology
Carl-Neuberg-Str. 1
30625 Hannover

Germany

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Project Leader


Prof. Dr. med. Jens Jordan Prof. Dr. med. Jens Jordan
Project Leader 
Phone: +49-(0)511 532 2821 
Fax: +49-(0)511 532 2750 
E-Mail to Prof. Dr. med. Jens Jordan Contact  



Project Staff


PD Dr. med. Dipl.-Biol. Stefan Engeli PD Dr. med. Dipl.-Biol. Stefan Engeli
Group Leader 
Phone: +49-(0)511 532 2796 
Fax: +49-(0)511 532 2750 
E-Mail to PD Dr. med. Dipl.-Biol. Stefan Engeli Contact  

Bibiana Beckmann Bibiana Beckmann
Technician (Cell and Molecular Biology) 


Institute Presentation


Jens Jordan is Director of the Institute of Clinical Pharmacology, Hannover Medical School, Germany, since April 2008. He published more than 100 original contributions in peer reviewed journals. His research focuses on metabolic and cardiovascular regulation and mechanisms of obesity-associated cardiovascular disease in human subjects. Prof. Jordan was founder of the Franz-Volhard-Clinical Research Center at the University Clinic Charité in Berlin, which was one of the leading facilities for metabolic and cardiovascular patient oriented research in Germany. At the Hannover Medical School, he is now heading a fully equipped academic clinical research center. Furthermore, the institute has a strong background in biomarker and drug analysis (HPLC, GC-MS/MS; LC-MS/MS) with a focus on oxidative stress, NO metabolism, prostaglandins, and endocannabinoids. The laboratory of adipocyte and skeletal muscle physiology is supervised by Dr. Engeli. He has a longstanding experience in characterizing human adipose tissue samples from clinical studies (more than 30 original contributions in peer reviewed journals). Substantial research on the lipolytic effects of the atrial natriuretic peptide in vivo was performed by Prof. Jordan and his co-workers. Prof. Jordan and Dr. Engeli participate in the ADAPT consortium (HEALTH-F2-2008-201100) which focuses on adipokine research. Their contribution is on epicardial adipose tissue in relationship to cardiac function and adipokine production in obese subjects. In this study, cardiac MRI is combined with MRI imaging and spectroscopy of adipose tissue, liver, and skeletal muscle in >180 obese women and men (cross-sectional study) and >90 obese women and men after weight loss (longitudinal study for 1 year). These data will also contribute to the understanding of heart function as addressed in the SICA-HF consortium.

 


Medizinische Hochschule Hannover