
Institute of Cardiology, Siberian Branch, Russian Academy of Medical Sciences
Kievskaya str., 111A
634012 Tomsk
Russian Federation
Homepage
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Prof. Rostislav Karpov Project Leader Phone: +7 (0) 382 2 553449 Fax: +7 (0) 382 2 555057 |
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Prof. Sergey Afanasiev Head of the Molecular and Cellular Pathology and Gene Diagnostics Laboratory |
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Tatiana Suslova Leading Research Fellow, Functional and Laboratory Diagnostics Department |
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Prof. Olga Koshelskaya Leading Research Fellow of the Atherosclerosis and Chronic Ischemic Heart Disease Department |
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Prof. Sergey Popov Head of the Surgical Treatment of the Complicated Heart Rhythm Disturbances and Electrocardiostimulation Department |
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Dina Kondratieva Research Fellow |
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Oksana Ogurkova Research Fellow |
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Tatjana Rebrova Research Fellow |
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Irina Kologrivova Research Fellow |
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Ekaterina Levashkina Junior Research Fellow |
Several departments of the Institute of Cardiology are participating in the project:
Laboratory molecular and cell pathology and gene diagnostic: Participants of the project have a long-term experience in electrophysiological research of the human and animal (rat) myocardium. Functional heterogeneity of human failing heart was studied extensively in our laboratory. Comparative research of myocardium of patients with heart failure of a different etiology was performed. Ambiguous alteration of sarcoplasmic reticulum function of myocardium of patients at the development heart failure was obtained, and an assumption of existence of various ways of myocardium adaptation to damaging factors was made. Our preliminary results showed that development of heart failure is accompanied with sarcoplasmic reticulum dysfunction.
Functional and Laboratory Diagnostics Department is specialized on studying of proinflammatory factors, oxygen-dependent processes in platelets, mononuclear leucocytes and oxidative resistance of lipoproteins at metabolic syndrome. The research is focused on the study of cellular and molecular mechanisms of platelet aggregation activity disturbances during the association of diabetes mellitus, ischemic heart disease and heart failure.
Department of Atherosclerosis and Chronic Ischemic Heart Disease of Tomsk Institute of Cardiology accumulated a huge knowledge of diagnostics, treatment and prevention of cardio-vascular pathologies, including chronic heart failure and such co-morbidities as metabolic syndrome, diabetes mellitus, and obesity, in patients from Siberia and neighbor regions: the Far East, Middle Asia and Kazakhstan. Being organized as one of the leading departments of the Institute, it possesses a 25-year experience in experimental and clinical cardiology.